憨豆精神 发表于 2012-5-12 16:07 static/image/common/back.gif
最新消息：
经搜寻了解，目前国内所有医院并无此项检查业务开展，原来搜索出的信息只是国内某些医院做的研 ...
怎么参与？我父亲是AFP不敏感的
本帖最后由 lostm 于 2013-7-28 07:50 编辑
asco2013的最新结果
表明DCP和AFP都可用于鉴别HCC与ICC。
其中DCP性能更好。
http://meetinglibrary.asco.org/content/113496-132
Background: Differential diagnosis of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) can be challenging in patients without evidence of liver cirrhosis. Definitive diagnosis is based on tissue biopsy. We investigated if the use of serum biomarkers could help differentiate between these two types of malignancies, thereby avoiding the risks associated with biopsy. Methods: Patients with cholangiocarcinoma and HCC were recruited from Queen Elizabeth Hospital, Birmingham, UK; blood samples were collected at time of diagnosis. Two biomarkers, alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) were measured in the serum samples from 56 patients with cholangiocarcinoma and 35 patients with HCC without evidence of liver cirrhosis. Of the 56 patients with cholangiocarcinoma, 17 were intrahepatic and 39 were extrahepatic. Results: 17 ICC and 35 HCC were included in the analysis. The levels of AFP and DCP were much higher in HCC as compared to ICC. The median AFP was 64.6 (IQR 10.9, 3564.2) in HCC as compared to 3 (IQR 2.4, 3.9) in ICC. Similarly, the median DCP was 215.41 (IQR 22.46, 692.53) in HCC as compared to 0.33 (IQR 0.16, 1.08) in ICC. Stepwise logistic regression was performed using both biomarkers. Log- DCP remained significant at 95% level in predicting HCC from ICC, giving an AUC of 0.96. Conclusions: In patients with a non-cirrhotic liver and radiological evidence of cancer, measurement of serum AFP and DCP level may help differentiate between HCC and ICC. In this study, DCP is the most useful discriminator between HCC and ICC. Further prospective studies should be done with larger sample sizes to validate the use of AFP and DCP as diagnostic biomarkers in this clinical setting.
我侄子在上海的一家日本医院里测过，送日本检测
zhouhuinj 发表于 2013-5-23 12:31 static/image/common/back.gif
我侄子在上海的一家日本医院里测过，送日本检测
请问上海的那家日本医院是什么医院，我们家的AFP也不敏感，能否告知？
森茂诊料所
太姥香云 发表于 2013-8-1 22:10 static/image/common/back.gif
前天，给这家医院打过电话，他们说可以做，费用不超过1500
有电话号码吗？帮忙提供一下？谢谢！
要是在中国能做就太好了。我们这些不敏感病人就会安心些。
非常感谢！
我是刚看到这个帖，后悔 至极。
家不在上海的要做这项检测太难了